Christian Kirk hurt his groin on the first snap for the Jacksonville Jaguars in Monday night's game against Cincinnati Bengals.
Quarterback Trevor Lawrence picked Kirk out with a 26-yard pass and the wide receiver was wide open as he leapt up and took the catch.
But he landed awkwardly and stayed down, rolling in pain before eventually limping off the field and back to the locker room.
He was listed as questionable to return with concerns of a muscle injury.
The Jags then scored a touchdown on the drive through Travis Etienne to take an early lead in the game.
But a significant injury to Kirk would be a major blow to the Jaguars who have got better and better as the NFL season has gone on.
The team lost two of their first three games of the season, against Kansas City Chiefs and Houston Texans, before winning seven of the next eight.
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