Twist in case of Melbourne woman who went missing after her car broke down on a country highway

A woman who went missing after her car broke down may have already returned to Melbourne but has still has not made contact with her family. 

Point Cook woman Samantha, 33, was last seen when her grey Kia Sportage broke down on the Princes Highway in Tamboon at about 8.15am on Friday. 

Police now believe Samantha may have travelled from Bairnsdale, in Victoria's East Gippsland region, to Melbourne by train later on the Friday. 

She may have been at a shopping centre in Centreway in Mount Waverley. 

Police say they are concerned for the missing woman due to a medical condition she has and say her disappearance is out of character.

It was initially believed Samantha may have disappeared while hitch-hiking.

She was last seen wearing a blue/grey fleece, jeans and runners. 

A search was launched in Tamboon with help from the SES on Sunday. 

Anyone with information has been urged to contact Bairnsdale Police Station.